HSV-2 triggers upregulation of MALAT1 in CD4(+) T cells and promotes HIV latency reversal

Herpes simplex virus type 2 (HSV-2) coinfection is associated with increased HIV-1 viral loads and expanded tissue reservoirs, but the mechanisms are not well defined. HSV-2 recurrences result in an influx of activated CD4(+) T cells to sites of viral replication and an increase in activated CD4(+)...

Descripción completa

Detalles Bibliográficos
Autores principales: Pierce, Carl A., Loh, Lip Nam, Steach, Holly R., Cheshenko, Natalia, Preston-Hurlburt, Paula, Zhang, Fengrui, Stransky, Stephanie, Kravets, Leah, Sidoli, Simone, Philbrick, William, Nassar, Michel, Krishnaswamy, Smita, Herold, Kevan C., Herold, Betsy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232005/
https://www.ncbi.nlm.nih.gov/pubmed/37079384
http://dx.doi.org/10.1172/JCI164317

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232005/
https://www.ncbi.nlm.nih.gov/pubmed/37079384
http://dx.doi.org/10.1172/JCI164317

Ejemplares similares