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ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through Autophagy
Skeletal muscle regeneration after injury is essential for maintaining muscle function throughout aging. ARHGEF3, a RhoA/B-specific GEF, negatively regulates myoblast differentiation through Akt signaling independently of its GEF activity in vitro. Here, we report ARHGEF3’s role in skeletal muscle r...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232017/ https://www.ncbi.nlm.nih.gov/pubmed/33406419 http://dx.doi.org/10.1016/j.celrep.2020.108594 |