ARHGEF3 Regulates Skeletal Muscle Regeneration and Strength through Autophagy

Skeletal muscle regeneration after injury is essential for maintaining muscle function throughout aging. ARHGEF3, a RhoA/B-specific GEF, negatively regulates myoblast differentiation through Akt signaling independently of its GEF activity in vitro. Here, we report ARHGEF3’s role in skeletal muscle r...

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Detalles Bibliográficos
Autores principales: You, Jae-Sung, Singh, Nilmani, Reyes-Ordonez, Adriana, Khanna, Nidhi, Bao, Zehua, Zhao, Huimin, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232017/
https://www.ncbi.nlm.nih.gov/pubmed/33406419
http://dx.doi.org/10.1016/j.celrep.2020.108594

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