Mosaic loss of Y chromosome in monocytes is associated with lower survival after transcatheter aortic valve replacement

AIMS: Mosaic loss of Y chromosome (LOY) in blood cells is the most common acquired mutation, increases with age, and is related to cardiovascular disease. Loss of Y chromosome induces cardiac fibrosis in murine experiments mimicking the consequences of aortic valve stenosis, the prototypical age-rel...

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Detalles Bibliográficos
Autores principales: Mas-Peiro, Silvia, Abplanalp, Wesley T, Rasper, Tina, Berkowitsch, Alexander, Leistner, David M, Dimmeler, Stefanie, Zeiher, Andreas M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232276/
https://www.ncbi.nlm.nih.gov/pubmed/36932691
http://dx.doi.org/10.1093/eurheartj/ehad093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232276/
https://www.ncbi.nlm.nih.gov/pubmed/36932691
http://dx.doi.org/10.1093/eurheartj/ehad093

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