Seed amplification and neurodegeneration marker trajectories in individuals at risk of prion disease

Human prion diseases are remarkable for long incubation times followed typically by rapid clinical decline. Seed amplification assays and neurodegeneration biofluid biomarkers are remarkably useful in the clinical phase, but their potential to predict clinical onset in healthy people remains unclear...

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Detalles Bibliográficos
Autores principales: Mok, Tze How, Nihat, Akin, Majbour, Nour, Sequeira, Danielle, Holm-Mercer, Leah, Coysh, Thomas, Darwent, Lee, Batchelor, Mark, Groveman, Bradley R, Orr, Christina D, Hughson, Andrew G, Heslegrave, Amanda, Laban, Rhiannon, Veleva, Elena, Paterson, Ross W, Keshavan, Ashvini, Schott, Jonathan M, Swift, Imogen J, Heller, Carolin, Rohrer, Jonathan D, Gerhard, Alexander, Butler, Christopher, Rowe, James B, Masellis, Mario, Chapman, Miles, Lunn, Michael P, Bieschke, Jan, Jackson, Graham S, Zetterberg, Henrik, Caughey, Byron, Rudge, Peter, Collinge, John, Mead, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232278/
https://www.ncbi.nlm.nih.gov/pubmed/36975162
http://dx.doi.org/10.1093/brain/awad101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232278/
https://www.ncbi.nlm.nih.gov/pubmed/36975162
http://dx.doi.org/10.1093/brain/awad101

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