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TRPM2 Mediates Hepatic Ischemia–Reperfusion Injury via Ca(2+)-Induced Mitochondrial Lipid Peroxidation through Increasing ALOX12 Expression
Hepatic ischemia–reperfusion (IR) injury is a serious clinical problem that complicates liver resection and transplantation. Despite recent advances in understanding of the pathophysiology of hepatic IR injury, effective interventions and therapeutics are still lacking. Here, we examined the role of...
Autores principales: | Zhong, Cheng, Yang, Jing, Zhang, Yiyin, Fan, Xiaoxiao, Fan, Yang, Hua, Ning, Li, Duguang, Jin, Shengxi, Li, Yirun, Chen, Peng, Chen, Yongle, Cai, Xiaobo, Zhang, Yi, Jiang, Linhua, Yang, Wei, Yu, Peilin, Lin, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAAS
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232356/ https://www.ncbi.nlm.nih.gov/pubmed/37275121 http://dx.doi.org/10.34133/research.0159 |
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