Anticancer efficacy of hirsuteine against colorectal cancer by opposite modulation of wild-type and mutant p53

PURPOSE: The present study aimed to explore the anticancer activity of hirsuteine (HST), an indole alkaloid from the traditional Chinese herbal medicine Uncaria rhynchophylla, against colorectal cancer (CRC) and the underlining mechanism. METHODS: MTT, colony formation, flow cytometry and MDC staini...

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Detalles Bibliográficos
Autores principales: Zhang, Yan, Guo, Tingting, Li, Shurong, Ren, Zehao, Gao, Shan, Lu, Hao, Ma, Xuelan, Liu, Donghui, Liu, Yao, Kong, Dexin, Qiu, Yuling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232392/
https://www.ncbi.nlm.nih.gov/pubmed/37256374
http://dx.doi.org/10.1007/s12672-023-00688-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232392/
https://www.ncbi.nlm.nih.gov/pubmed/37256374
http://dx.doi.org/10.1007/s12672-023-00688-1

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