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Leukemia relapse via genetic immune escape after allogeneic hematopoietic cell transplantation

Graft-versus-leukemia (GvL) reactions are responsible for the effectiveness of allogeneic hematopoietic cell transplantation as a treatment modality for myeloid neoplasia, whereby donor T- effector cells recognize leukemia neoantigens. However, a substantial fraction of patients experiences relapses...

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Detalles Bibliográficos
Autores principales: Pagliuca, Simona, Gurnari, Carmelo, Hercus, Colin, Hergalant, Sébastien, Hong, Sanghee, Dhuyser, Adele, D’Aveni, Maud, Aarnink, Alice, Rubio, Marie Thérèse, Feugier, Pierre, Ferraro, Francesca, Carraway, Hetty E., Sobecks, Ronald, Hamilton, Betty K., Majhail, Navneet S., Visconte, Valeria, Maciejewski, Jaroslaw P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232425/
https://www.ncbi.nlm.nih.gov/pubmed/37258544
http://dx.doi.org/10.1038/s41467-023-38113-4