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Hypoxia-induced reprogramming of glucose-dependent metabolic pathways maintains the stemness of human bone marrow-derived endothelial progenitor cells

The benefits of hypoxia for maintaining the stemness of cultured human bone marrow-derived endothelial progenitor cells (BM EPCs) have previously been demonstrated but the mechanisms responsible remain unclear. Growing evidences suggest that cellular metabolism plays an important role in regulating...

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Detalles Bibliográficos
Autores principales: Lin, Dongni, Yan, Kaihao, Chen, Lingyun, Chen, Junxiong, Xu, Jianing, Xie, Zijing, Li, Zhujun, Lin, Shuo, Li, Jinghuan, Chen, Zhenzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232473/
https://www.ncbi.nlm.nih.gov/pubmed/37258701
http://dx.doi.org/10.1038/s41598-023-36007-5