GPX4 overexpressed non-small cell lung cancer cells are sensitive to RSL3-induced ferroptosis

Ferroptosis can be induced by inhibiting antioxidant enzymes GPX4 or system Xc(−), increased intracellular iron concentrations, and lipid peroxidation. Recently, it has been suggested that ferroptosis can be an effective way to induce cancer cell death, although the specific relevance and mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Joo-Won, Min, Dong Wha, Kim, Dasom, Kim, Joohee, Kim, Min Jung, Lim, Hyangsoon, Lee, Ji-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232506/
https://www.ncbi.nlm.nih.gov/pubmed/37258589
http://dx.doi.org/10.1038/s41598-023-35978-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232506/
https://www.ncbi.nlm.nih.gov/pubmed/37258589
http://dx.doi.org/10.1038/s41598-023-35978-9

Ejemplares similares