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Genome-wide profiling of patient-derived glioblastoma stem-like cells reveals recurrent genetic and transcriptomic signatures associated with brain tumors

PURPOSE: Patient-derived cancer cell lines can be very useful to investigate genetic as well as epigenetic mechanisms of transformation and to test new drugs. In this multi-centric study, we performed genomic and transcriptomic characterization of a large set of patient-derived glioblastoma (GBM) st...

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Detalles Bibliográficos
Autores principales: Lazzarini, Elisabetta, Silvestris, Domenico Alessandro, Benvenuto, Giuseppe, Osti, Daniela, Fattore, Luigi, Paterra, Rosina, Finocchiaro, Gaetano, Malatesta, Paolo, Daga, Antonio, Gallotti, Alberto L., Galli, Rossella, Pelicci, Giuliana, Tesei, Anna, Bedeschi, Martina, Pallini, Roberto, Pasqualini, Lorenza, Romualdi, Chiara, Gallo, Angela, Ricci-Vitiani, Lucia, Indraccolo, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232615/
https://www.ncbi.nlm.nih.gov/pubmed/37140883
http://dx.doi.org/10.1007/s11060-023-04287-6