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Discovery of a natural small-molecule AMP-activated kinase activator that alleviates nonalcoholic steatohepatitis
Non-alcoholic steatohepatitis (NASH) is a primary cause of cirrhosis and hepatocellular carcinoma. Unfortunately, there is no approved drug treatment for NASH. AMP-activated kinase (AMPK) is an important metabolic sensor and whole-body regulator. It has been proposed that AMPK activators could be us...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232707/ https://www.ncbi.nlm.nih.gov/pubmed/37275542 http://dx.doi.org/10.1007/s42995-023-00168-z |