Discovery of a natural small-molecule AMP-activated kinase activator that alleviates nonalcoholic steatohepatitis

Non-alcoholic steatohepatitis (NASH) is a primary cause of cirrhosis and hepatocellular carcinoma. Unfortunately, there is no approved drug treatment for NASH. AMP-activated kinase (AMPK) is an important metabolic sensor and whole-body regulator. It has been proposed that AMPK activators could be us...

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Detalles Bibliográficos
Autores principales: Chen, Jin, Xu, Li, Zhang, Xue-Qing, Liu, Xue, Zhang, Zi-Xuan, Zhu, Qiu-Mei, Liu, Jian-Yu, Iqbal, Muhammad Omer, Ding, Ning, Shao, Chang-Lun, Wei, Mei-Yan, Gu, Yu-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232707/
https://www.ncbi.nlm.nih.gov/pubmed/37275542
http://dx.doi.org/10.1007/s42995-023-00168-z

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