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Zhx2 maintains islet β-cell mass and function by transcriptionally regulating Pax6

Emerging evidence shows that pancreatic β-cell function and quality are key determinants in the progression of type 2 diabetes (T2D). The transcription factor zinc finger homeobox 2 (Zhx2) is involved in proliferation and development of multiple cells. However, the exact role of Zhx2 in β-cells and...

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Detalles Bibliográficos
Autores principales: Ding, Lu, Zhang, Yankun, Wang, Yingchun, Wang, Yuzhen, Tong, Zheng, Li, Pengfei, Chen, Chaojia, Wang, Bo, Yue, Xuetian, Li, Chunyang, Wu, Zhuanchang, Liang, Xiaohong, Ma, Chunhong, Gao, Lifen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232729/
https://www.ncbi.nlm.nih.gov/pubmed/37275527
http://dx.doi.org/10.1016/j.isci.2023.106871