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Antagonistic interactions among structured domains in the multivalent Bicc1-ANKS3-ANKS6 protein network govern phase transitioning of target mRNAs

The growing number of diseases linked to aberrant phase transitioning of ribonucleoproteins highlights the need to uncover how the interplay between multivalent protein and RNA interactions is regulated. Cytoplasmic granules of the RNA binding protein Bicaudal-C (Bicc1) are regulated by the ciliopat...

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Detalles Bibliográficos
Autores principales: Rothé, Benjamin, Fortier, Simon, Gagnieux, Céline, Schmuziger, Céline, Constam, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232731/
https://www.ncbi.nlm.nih.gov/pubmed/37275520
http://dx.doi.org/10.1016/j.isci.2023.106855