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Bone marrow adipocytes alteration in an in vitro model of Gaucher Disease

Gaucher disease (GD) is caused by biallelic pathogenic variants in GBA1 gene that encodes the lysosomal enzyme glucocerebrosidase. Up to now, specific treatment for GD cannot completely reverse bone complications. Bone is composed of different cell types; including osteoblasts, osteocytes and osteoc...

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Detalles Bibliográficos
Autores principales: Crivaro, A., Mucci, J.M., Bondar, C., Ormazabal, M., Vaena, E., Delpino, M.V., Rozenfeld, P.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232844/
https://www.ncbi.nlm.nih.gov/pubmed/37275240
http://dx.doi.org/10.1016/j.ymgmr.2023.100980