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Gasdermin D-mediated pyroptosis: mechanisms, diseases, and inhibitors

Gasdermin D (GSDMD)-mediated pyroptosis and downstream inflammation are important self-protection mechanisms against stimuli and infections. Hosts can defend against intracellular bacterial infections by inducing cell pyroptosis, which triggers the clearance of pathogens. However, pyroptosis is a do...

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Detalles Bibliográficos
Autores principales: Dai, Zhen, Liu, Wan-Cong, Chen, Xiao-Yi, Wang, Xiao, Li, Jun-Long, Zhang, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232970/
https://www.ncbi.nlm.nih.gov/pubmed/37275856
http://dx.doi.org/10.3389/fimmu.2023.1178662