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The development of CD8 T-cell exhaustion heterogeneity and the therapeutic potentials in cancer
CD8(+) T cells are essential lymphocytes with cytotoxic properties for antitumor immunotherapy. However, during chronic infection or tumorigenesis, these cells often become dysfunctional with a gradually depleted ability to release cytokines and the exhibition of reduced cytotoxicity, the state refe...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10232978/ https://www.ncbi.nlm.nih.gov/pubmed/37275913 http://dx.doi.org/10.3389/fimmu.2023.1166128 |