Loss of cholinergic receptor muscarinic 1 impairs cortical mitochondrial structure and function: implications in Alzheimer’s disease

Introduction: Cholinergic Receptor Muscarinic 1 (CHRM1) is a G protein-coupled acetylcholine (ACh) receptor predominantly expressed in the cerebral cortex. In a retrospective postmortem brain tissues-based study, we demonstrated that severely (≥50% decrease) reduced CHRM1 proteins in the temporal co...

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Detalles Bibliográficos
Autores principales: Sabbir, Mohammad Golam, Swanson, Mamiko, Albensi, Benedict C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233041/
https://www.ncbi.nlm.nih.gov/pubmed/37274741
http://dx.doi.org/10.3389/fcell.2023.1158604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233041/
https://www.ncbi.nlm.nih.gov/pubmed/37274741
http://dx.doi.org/10.3389/fcell.2023.1158604

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