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Regeneration of T cells from human-induced pluripotent stem cells for CAR-T cell medicated immunotherapy
Background: Chimeric antigen receptor (CAR) T cell treatment involves in vitro production of T cells from patient blood with synthetic receptors specific to a cancer antigen. They circumvent the major histocompatibility complex to recognize the tumor antigen, reducing hematologic malignancy remissio...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233047/ https://www.ncbi.nlm.nih.gov/pubmed/37274170 http://dx.doi.org/10.3389/fbioe.2023.1159507 |