A masked, placebo-controlled, randomized clinical trial evaluating safety and the effect on cardiac function of low-dose rapamycin in 17 healthy client-owned dogs

INTRODUCTION: Geroscience studies of low-dose rapamycin in laboratory species have identified numerous benefits, including reversing age-related cardiac dysfunction. Cardiovascular benefits have been observed in dogs with 10 weeks of treatment, raising questions about possible benefits and adverse e...

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Detalles Bibliográficos
Autores principales: Barnett, Brian G., Wesselowski, Sonya R., Gordon, Sonya G., Saunders, Ashley B., Promislow, Daniel E. L., Schwartz, Stephen M., Chou, Lucy, Evans, Jeremy B., Kaeberlein, Matt, Creevy, Kate E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233048/
https://www.ncbi.nlm.nih.gov/pubmed/37275618
http://dx.doi.org/10.3389/fvets.2023.1168711

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233048/
https://www.ncbi.nlm.nih.gov/pubmed/37275618
http://dx.doi.org/10.3389/fvets.2023.1168711

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