Cargando…
A masked, placebo-controlled, randomized clinical trial evaluating safety and the effect on cardiac function of low-dose rapamycin in 17 healthy client-owned dogs
INTRODUCTION: Geroscience studies of low-dose rapamycin in laboratory species have identified numerous benefits, including reversing age-related cardiac dysfunction. Cardiovascular benefits have been observed in dogs with 10 weeks of treatment, raising questions about possible benefits and adverse e...
Autores principales: | Barnett, Brian G., Wesselowski, Sonya R., Gordon, Sonya G., Saunders, Ashley B., Promislow, Daniel E. L., Schwartz, Stephen M., Chou, Lucy, Evans, Jeremy B., Kaeberlein, Matt, Creevy, Kate E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233048/ https://www.ncbi.nlm.nih.gov/pubmed/37275618 http://dx.doi.org/10.3389/fvets.2023.1168711 |
Ejemplares similares
-
Reasons for Exclusion of Apparently Healthy Mature Adult and Senior Dogs From a Clinical Trial
por: Gibbs, Nicole H., et al.
Publicado: (2021) -
Anatomy, baseline characteristics, and procedural outcome of patent ductus arteriosus in German Shepherd dogs
por: Wesselowski, Sonya, et al.
Publicado: (2018) -
Intracardiac heartworms in dogs: Clinical and echocardiographic characteristics in 72 cases (2010‐2019)
por: Romano, Abigail E., et al.
Publicado: (2020) -
Rapamycin enhances survival in a Drosophila model of mitochondrial disease
por: Wang, Adrienne, et al.
Publicado: (2016) -
Lifespan of companion dogs seen in three independent primary care veterinary clinics in the United States
por: Urfer, Silvan R., et al.
Publicado: (2020)