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Mycobacterial-specific secretion of cytokines and chemokines in healthcare workers with apparent resistance to infection with Mycobacterium tuberculosis

BACKGROUND: Currently, diagnosis of latent TB infection (LTBI) is based on the secretion of IFN-γ in response to Mycobacterium tuberculosis (Mtb) antigens, the absence of which is regarded as no infection. Some individuals appear to resist Mtb infection despite sustained exposure (resisters). In thi...

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Detalles Bibliográficos
Autores principales: Shey, Muki Shehu, Balfour, Avuyonke, Masina, Nomawethu, Bekiswa, Abulele, Schutz, Charlotte, Goliath, Rene, Dielle, Rachel, Katoto, Patrick DMC., Wilkinson, Katalin Andrea, Lewinsohn, David, Lewinsohn, Deborah Anne, Meintjes, Graeme
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233115/
https://www.ncbi.nlm.nih.gov/pubmed/37275871
http://dx.doi.org/10.3389/fimmu.2023.1176615