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An in silico approach to identify early damage biomarker candidates in metachromatic leukodystrophy

Metachromatic leukodystrophy (MLD) is a rare, autosomal recessive lysosomal storage disease. Deficient activity of arylsulfatase A causes sulfatides to accumulate in cells of different tissues, including those in the central and peripheral nervous systems, leading to progressive demyelination and ne...

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Detalles Bibliográficos
Autores principales: Gómez, Jessica, Artigas, Laura, Valls, Raquel, Gervas-Arruga, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233284/
https://www.ncbi.nlm.nih.gov/pubmed/37275681
http://dx.doi.org/10.1016/j.ymgmr.2023.100974