Znf469 Plays a Critical Role in Regulating Synthesis of ECM: A Zebrafish Model of Brittle Cornea Syndrome

PURPOSE: Brittle cornea syndrome (BCS) is a rare autosomal recessive disorder characterized by extreme thinning and fragility of the cornea, and mutations in ZNF469 cause BCS-1. We aimed to establish a znf469 mutant zebrafish line to explore its roles and possible pathogenic mechanism in cornea deve...

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Detalles Bibliográficos
Autores principales: Bao, Jing, Yu, Xiaoning, Ping, Xiyuan, Shentu, Xingchao, Zou, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233312/
https://www.ncbi.nlm.nih.gov/pubmed/37256609
http://dx.doi.org/10.1167/iovs.64.5.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233312/
https://www.ncbi.nlm.nih.gov/pubmed/37256609
http://dx.doi.org/10.1167/iovs.64.5.29

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