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Polygenic Risk Score in African populations: progress and challenges

Polygenic Risk Score (PRS) analysis is a method that predicts the genetic risk of an individual towards targeted traits. Even when there are no significant markers, it gives evidence of a genetic effect beyond the results of Genome-Wide Association Studies (GWAS). Moreover, it selects  single nucleo...

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Detalles Bibliográficos
Autores principales: Adam, Yagoub, Sadeeq, Suraju, Kumuthini, Judit, Ajayi, Olabode, Wells, Gordon, Solomon, Rotimi, Ogunlana, Olubanke, Adetiba, Emmanuel, Iweala, Emeka, Brors, Benedikt, Adebiyi, Ezekiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233318/
https://www.ncbi.nlm.nih.gov/pubmed/37273966
http://dx.doi.org/10.12688/f1000research.76218.2