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A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer

PURPOSE: The oncogenic role of circular RNAs (circRNA) has been well studied in cancers including colorectal cancer. However, tumor-suppressive circRNAs and the mechanism through which they exert their antitumor effects remain largely unknown. We aim to find out the critical tumor-suppressive circRN...

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Detalles Bibliográficos
Autores principales: Ding, Nan, You, A-Bin, Yang, Hu, Hu, Guo-Sheng, Lai, Chun-Ping, Liu, Wen, Ye, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233356/
https://www.ncbi.nlm.nih.gov/pubmed/36951687
http://dx.doi.org/10.1158/1078-0432.CCR-22-3836