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A systematic proximity ligation approach to studying protein‐substrate specificity identifies the substrate spectrum of the Ssh1 translocon

Many cellular functions are carried out by protein pairs or families, providing robustness alongside functional diversity. For such processes, it remains a challenge to map the degree of specificity versus promiscuity. Protein–protein interactions (PPIs) can be used to inform on these matters as the...

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Detalles Bibliográficos
Autores principales: Cohen, Nir, Aviram, Naama, Schuldiner, Maya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233368/
https://www.ncbi.nlm.nih.gov/pubmed/37073826
http://dx.doi.org/10.15252/embj.2022113385