An ERK1/2‐driven RNA‐binding switch in nucleolin drives ribosome biogenesis and pancreatic tumorigenesis downstream of RAS oncogene

Oncogenic RAS signaling reprograms gene expression through both transcriptional and post‐transcriptional mechanisms. While transcriptional regulation downstream of RAS is relatively well characterized, how RAS post‐transcriptionally modulates gene expression to promote malignancy remains largely unc...

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Detalles Bibliográficos
Autores principales: Azman, Muhammad S, Alard, Emilie L, Dodel, Martin, Capraro, Federica, Faraway, Rupert, Dermit, Maria, Fan, Wanling, Chakraborty, Alina, Ule, Jernej, Mardakheh, Faraz K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233377/
https://www.ncbi.nlm.nih.gov/pubmed/37039106
http://dx.doi.org/10.15252/embj.2022110902

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233377/
https://www.ncbi.nlm.nih.gov/pubmed/37039106
http://dx.doi.org/10.15252/embj.2022110902

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