Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl‐CoA

Changes in mitochondrial morphology are associated with nutrient utilization, but the precise causalities and the underlying mechanisms remain unknown. Here, using cellular models representing a wide variety of mitochondrial shapes, we show a strong linear correlation between mitochondrial fragmenta...

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Detalles Bibliográficos
Autores principales: Ngo, Jennifer, Choi, Dong Wook, Stanley, Illana A, Stiles, Linsey, Molina, Anthony J A, Chen, Pei‐Hsuan, Lako, Ana, Sung, Isabelle Chiao Han, Goswami, Rishov, Kim, Min‐young, Miller, Nathanael, Baghdasarian, Siyouneh, Kim‐Vasquez, Doyeon, Jones, Anthony E, Roach, Brett, Gutierrez, Vincent, Erion, Karel, Divakaruni, Ajit S, Liesa, Marc, Danial, Nika N, Shirihai, Orian S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233380/
https://www.ncbi.nlm.nih.gov/pubmed/36917141
http://dx.doi.org/10.15252/embj.2022111901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233380/
https://www.ncbi.nlm.nih.gov/pubmed/36917141
http://dx.doi.org/10.15252/embj.2022111901

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