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Mitochondrial morphology controls fatty acid utilization by changing CPT1 sensitivity to malonyl‐CoA
Changes in mitochondrial morphology are associated with nutrient utilization, but the precise causalities and the underlying mechanisms remain unknown. Here, using cellular models representing a wide variety of mitochondrial shapes, we show a strong linear correlation between mitochondrial fragmenta...
Autores principales: | Ngo, Jennifer, Choi, Dong Wook, Stanley, Illana A, Stiles, Linsey, Molina, Anthony J A, Chen, Pei‐Hsuan, Lako, Ana, Sung, Isabelle Chiao Han, Goswami, Rishov, Kim, Min‐young, Miller, Nathanael, Baghdasarian, Siyouneh, Kim‐Vasquez, Doyeon, Jones, Anthony E, Roach, Brett, Gutierrez, Vincent, Erion, Karel, Divakaruni, Ajit S, Liesa, Marc, Danial, Nika N, Shirihai, Orian S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233380/ https://www.ncbi.nlm.nih.gov/pubmed/36917141 http://dx.doi.org/10.15252/embj.2022111901 |
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