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The Ebola virus VP40 matrix layer undergoes endosomal disassembly essential for membrane fusion

Ebola viruses (EBOVs) assemble into filamentous virions, whose shape and stability are determined by the matrix viral protein 40 (VP40). Virus entry into host cells occurs via membrane fusion in late endosomes; however, the mechanism of how the remarkably long virions undergo uncoating, including vi...

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Detalles Bibliográficos
Autores principales: Winter, Sophie L, Golani, Gonen, Lolicato, Fabio, Vallbracht, Melina, Thiyagarajah, Keerthihan, Ahmed, Samy Sid, Lüchtenborg, Christian, Fackler, Oliver T, Brügger, Britta, Hoenen, Thomas, Nickel, Walter, Schwarz, Ulrich S, Chlanda, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233383/
https://www.ncbi.nlm.nih.gov/pubmed/37082863
http://dx.doi.org/10.15252/embj.2023113578