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The Ebola virus VP40 matrix layer undergoes endosomal disassembly essential for membrane fusion
Ebola viruses (EBOVs) assemble into filamentous virions, whose shape and stability are determined by the matrix viral protein 40 (VP40). Virus entry into host cells occurs via membrane fusion in late endosomes; however, the mechanism of how the remarkably long virions undergo uncoating, including vi...
Autores principales: | Winter, Sophie L, Golani, Gonen, Lolicato, Fabio, Vallbracht, Melina, Thiyagarajah, Keerthihan, Ahmed, Samy Sid, Lüchtenborg, Christian, Fackler, Oliver T, Brügger, Britta, Hoenen, Thomas, Nickel, Walter, Schwarz, Ulrich S, Chlanda, Petr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233383/ https://www.ncbi.nlm.nih.gov/pubmed/37082863 http://dx.doi.org/10.15252/embj.2023113578 |
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