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Structural modeling of Na(v)1.5 pore domain in closed state

The voltage-dependent cardiac sodium channel plays a key role in cardiac excitability and conduction and it is the drug target of medically important. However, its atomic- resolution structure is still lack. Here, we report a modeled structure of Na(v)1.5 pore domain in closed state. The structure w...

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Detalles Bibliográficos
Autores principales: Ji, Xiaofeng, Huang, Yanzhao, Sheng, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biophysics Reports Editorial Office 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233475/
https://www.ncbi.nlm.nih.gov/pubmed/37287760
http://dx.doi.org/10.52601/bpr.2021.200021