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TopFD: A Proteoform Feature Detection Tool for Top–Down Proteomics

[Image: see text] Top-down liquid chromatography-mass spectrometry (LC-MS) analyzes intact proteoforms and generates mass spectra containing peaks of proteoforms with various isotopic compositions, charge states, and retention times. An essential step in top-down MS data analysis is proteoform featu...

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Detalles Bibliográficos
Autores principales: Basharat, Abdul Rehman, Zang, Yong, Sun, Liangliang, Liu, Xiaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233584/
https://www.ncbi.nlm.nih.gov/pubmed/37196155
http://dx.doi.org/10.1021/acs.analchem.2c05244