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TopFD: A Proteoform Feature Detection Tool for Top–Down Proteomics
[Image: see text] Top-down liquid chromatography-mass spectrometry (LC-MS) analyzes intact proteoforms and generates mass spectra containing peaks of proteoforms with various isotopic compositions, charge states, and retention times. An essential step in top-down MS data analysis is proteoform featu...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233584/ https://www.ncbi.nlm.nih.gov/pubmed/37196155 http://dx.doi.org/10.1021/acs.analchem.2c05244 |