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Cysteine synthase: multiple structures of a key enzyme in cysteine synthesis and a potential drug target for Chagas disease and leishmaniasis

Chagas disease is a neglected tropical disease (NTD) caused by Trypanosoma cruzi, whilst leishmaniasis, which is caused by over 20 species of Leishmania, represents a group of NTDs endemic to most countries in the tropical and subtropical belt of the planet. These diseases remain a significant healt...

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Detalles Bibliográficos
Autores principales: Sowerby, Kate, Freitag-Pohl, Stefanie, Murillo, Ana Milena, Silber, Ariel Mariano, Pohl, Ehmke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233618/
https://www.ncbi.nlm.nih.gov/pubmed/37204818
http://dx.doi.org/10.1107/S2059798323003613