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The type III secretion chaperone SctY may shield the hydrophobic export gate-binding C-terminus of its substrate SctX

Gram-negative bacteria such as Aeromonas and Yersinia spp. have developed mechanisms to inhibit the immune defense of their host. Effector proteins are directly injected into the host cytoplasm from the bacterial cytosol via type III secretion systems (T3SSs), where they modulate the cytoskeleton an...

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Detalles Bibliográficos
Autores principales: Gilzer, Dominic, Kowal, Julia L., Flottmann, Franziska, Niemann, Hartmut H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233624/
https://www.ncbi.nlm.nih.gov/pubmed/37204817
http://dx.doi.org/10.1107/S2059798323003248