Evaluation of a Novel Combination Therapy, Based on Trifluridine/Tipiracil and Fruquintinib, against Colorectal Cancer

INTRODUCTION: Trifluridine/tipiracil hydrochloride (FTD/TPI, Lonsurf(®)) is an oral antineoplastic agent that has been approved as late-stage chemotherapy for colorectal cancer. Its major mechanism of action is the dysfunction of tumoral DNA including DNA strand breaks and decreased replication. Fru...

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Detalles Bibliográficos
Autores principales: Nukatsuka, Mamoru, Fujioka, Akio, Nagase, Hideki, Tanaka, Gotaro, Hayashi, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Anticancer Section / Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233702/
https://www.ncbi.nlm.nih.gov/pubmed/36623495
http://dx.doi.org/10.1159/000528867

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233702/
https://www.ncbi.nlm.nih.gov/pubmed/36623495
http://dx.doi.org/10.1159/000528867

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