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Evaluation of a Novel Combination Therapy, Based on Trifluridine/Tipiracil and Fruquintinib, against Colorectal Cancer
INTRODUCTION: Trifluridine/tipiracil hydrochloride (FTD/TPI, Lonsurf(®)) is an oral antineoplastic agent that has been approved as late-stage chemotherapy for colorectal cancer. Its major mechanism of action is the dysfunction of tumoral DNA including DNA strand breaks and decreased replication. Fru...
Autores principales: | Nukatsuka, Mamoru, Fujioka, Akio, Nagase, Hideki, Tanaka, Gotaro, Hayashi, Hiroaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233702/ https://www.ncbi.nlm.nih.gov/pubmed/36623495 http://dx.doi.org/10.1159/000528867 |
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