Silibinin, an HSP90 Inhibitor, on Human ACTH-Secreting Adenomas

INTRODUCTION: The glucocorticoid receptor is pivotal to control corticotrophin (ACTH) secretion, and its function is closely linked to the heat shock protein 90 (HSP90) chaperone complex. Impaired sensitivity to glucocorticoid feedback is a hallmark of human corticotroph adenomas, i.e., Cushing'...

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Detalles Bibliográficos
Autores principales: Pecori Giraldi, Francesca, Cassarino, Maria Francesca, Sesta, Antonella, Lasio, Giovanni, Losa, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233703/
https://www.ncbi.nlm.nih.gov/pubmed/36791678
http://dx.doi.org/10.1159/000529710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233703/
https://www.ncbi.nlm.nih.gov/pubmed/36791678
http://dx.doi.org/10.1159/000529710

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