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BRAF(V600E) Expression Is Homogenous and Associated with Nonrecurrent Disease and Better Survival in Primary Melanoma

BACKGROUND: Superficial spreading melanomas (SSMs) are the most common type of melanoma and cause the majority of skin cancer deaths. More than 50% of cases harbor a mutation in the BRAF gene that activates the mitogen-activated protein kinase (MAPK) cancer signaling pathway. BRAF(V600E) is the most...

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Detalles Bibliográficos
Autores principales: Naimy, Soraya, Bzorek, Michael, Eriksen, Jens Ole, Dyring-Andersen, Beatrice, Rahbek Gjerdrum, Lise Mette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233705/
https://www.ncbi.nlm.nih.gov/pubmed/36657398
http://dx.doi.org/10.1159/000528159