BMP4 triggers regulatory circuits specifying the cardiac mesoderm lineage

Cardiac lineage specification in the mouse is controlled by TGFβ and WNT signaling. From fly to fish, BMP has been identified as an indispensable heart inducer. A detailed analysis of the role of Bmp4 and its effectors Smad1/5, however, was still missing. We show that Bmp4 induces cardiac mesoderm f...

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Detalles Bibliográficos
Autores principales: Tsaytler, Pavel, Liu, Jinhua, Blaess, Gaby, Schifferl, Dennis, Veenvliet, Jesse V., Wittler, Lars, Timmermann, Bernd, Herrmann, Bernhard G., Koch, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Stem Cells and Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233716/
https://www.ncbi.nlm.nih.gov/pubmed/37082965
http://dx.doi.org/10.1242/dev.201450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233716/
https://www.ncbi.nlm.nih.gov/pubmed/37082965
http://dx.doi.org/10.1242/dev.201450

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