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Esrrγa regulates nephron and ciliary development by controlling prostaglandin synthesis

Cilia are essential for the ontogeny and function of many tissues, including the kidney. Here, we report that transcription factor ERRγ ortholog estrogen related receptor gamma a (Esrrγa) is essential for renal cell fate choice and ciliogenesis in zebrafish. esrrγa deficiency altered proximodistal n...

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Detalles Bibliográficos
Autores principales: Wesselman, Hannah M., Flores-Mireles, Ana L., Bauer, Aidan, Pei, Liming, Wingert, Rebecca A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233719/
https://www.ncbi.nlm.nih.gov/pubmed/37232416
http://dx.doi.org/10.1242/dev.201411