Suppressing high mobility group box-1 release alleviates morphine tolerance via the adenosine 5’-monophosphate-activated protein kinase/heme oxygenase-1 pathway

[Image: see text] Opioids, such as morphine, are the most potent drugs used to treat pain. Long-term use results in high tolerance to morphine. High mobility group box-1 (HMGB1) has been shown to participate in neuropathic or inflammatory pain, but its role in morphine tolerance is unclear. In this...

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Detalles Bibliográficos
Autores principales: Lin, Tong-Tong, Jiang, Chun-Yi, Sheng, Lei, Wan, Li, Fan, Wen, Li, Jin-Can, Sun, Xiao-Di, Xu, Chen-Jie, Hu, Liang, Wu, Xue-Feng, Han, Yuan, Liu, Wen-Tao, Pan, Yin-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233762/
https://www.ncbi.nlm.nih.gov/pubmed/36926733
http://dx.doi.org/10.4103/1673-5374.366490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233762/
https://www.ncbi.nlm.nih.gov/pubmed/36926733
http://dx.doi.org/10.4103/1673-5374.366490

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