Cargando…

Single-nuclei RNA sequencing uncovers heterogenous transcriptional signatures in Parkinson’s disease associated with nuclear receptor-related factor 1 defect

[Image: see text] Previous studies have found that deficiency in nuclear receptor-related factor 1 (Nurr1), which participates in the development, differentiation, survival, and degeneration of dopaminergic neurons, is associated with Parkinson’s disease, but the mechanism of action is perplexing. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Kambey, Piniel Alphayo, Liu, Wen-Ya, Wu, Jiao, Bosco, Bakwatanisa, Nadeem, Iqra, Kanwore, Kouminin, Gao, Dian-Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233763/
https://www.ncbi.nlm.nih.gov/pubmed/36926730
http://dx.doi.org/10.4103/1673-5374.366493