N-Acylated Ciprofloxacin Derivatives: Synthesis and In Vitro Biological Evaluation as Antibacterial and Anticancer Agents

[Image: see text] A novel series of N-acylated ciprofloxacin (CP) conjugates 1–21 were synthesized and screened as potential antimicrobial agents. Conjugates 1 and 2 were 1.25–10-fold more potent than CP toward all Staphylococci (minimal inhibitory concentration 0.05–0.4 μg/mL). Most of the chloro-...

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Detalles Bibliográficos
Autores principales: Struga, Marta, Roszkowski, Piotr, Bielenica, Anna, Otto-Ślusarczyk, Dagmara, Stępień, Karolina, Stefańska, Joanna, Zabost, Anna, Augustynowicz-Kopeć, Ewa, Koliński, Michał, Kmiecik, Sebastian, Myslovska, Alina, Wrzosek, Małgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233829/
https://www.ncbi.nlm.nih.gov/pubmed/37273589
http://dx.doi.org/10.1021/acsomega.3c00554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233829/
https://www.ncbi.nlm.nih.gov/pubmed/37273589
http://dx.doi.org/10.1021/acsomega.3c00554

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