Estrogen receptor alpha mutations regulate gene expression and cell growth in breast cancer through microRNAs

Estrogen receptor α (ER) mutations occur in up to 30% of metastatic ER-positive breast cancers. Recent data has shown that ER mutations impact the expression of thousands of genes not typically regulated by wildtype ER. While the majority of these altered genes can be explained by constant activity...

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Detalles Bibliográficos
Autores principales: Arnesen, Spencer, Polaski, Jacob T, Blanchard, Zannel, Osborne, Kyle S, Welm, Alana L, O’Connell, Ryan M, Gertz, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Cancer Gene Regulation, Chromatin, and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233889/
https://www.ncbi.nlm.nih.gov/pubmed/37275275
http://dx.doi.org/10.1093/narcan/zcad027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233889/
https://www.ncbi.nlm.nih.gov/pubmed/37275275
http://dx.doi.org/10.1093/narcan/zcad027

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