Metastatic lymph node targeted CTLA4 blockade: a potent intervention for local and distant metastases with minimal ICI-induced pneumonia

BACKGROUND: Immune checkpoint blockade (ICB) elicits a strong and durable therapeutic response, but its application is limited by disparate responses and its associated immune-related adverse events (irAEs). Previously, in a murine model of lymph node (LN) metastasis, we showed that intranodal admin...

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Detalles Bibliográficos
Autores principales: Mishra, Radhika, Sukhbaatar, Ariunbuyan, Mori, Shiro, Kodama, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233978/
https://www.ncbi.nlm.nih.gov/pubmed/37259163
http://dx.doi.org/10.1186/s13046-023-02645-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10233978/
https://www.ncbi.nlm.nih.gov/pubmed/37259163
http://dx.doi.org/10.1186/s13046-023-02645-w

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