Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration, proliferation, and signaling

BACKGROUND: Neuropeptide Y (NPY) is an abundant neurohormone in human breast carcinomas that acts on a class of G-protein coupled receptors, of which NPY1R and NPY5R are the most highly expressed. This abundance is exploited for cancer imaging, but there is interest in pharmacological inhibition of...

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Detalles Bibliográficos
Autores principales: Pascetta, Sydney A., Kirsh, Sarah M., Cameron, Makenna, Uniacke, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234023/
https://www.ncbi.nlm.nih.gov/pubmed/37264315
http://dx.doi.org/10.1186/s12885-023-10993-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234023/
https://www.ncbi.nlm.nih.gov/pubmed/37264315
http://dx.doi.org/10.1186/s12885-023-10993-1

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