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Cell-based optimization and characterization of genetically encoded location-based biosensors for Cdc42 or Rac activity
Rac (herein referring to the Rac family) and Cdc42 are Rho GTPases that regulate the formation of lamellipoda and filopodia, and are therefore crucial in processes such as cell migration. Relocation-based biosensors for Rac and Cdc42 have not been characterized well in terms of their specificity or...
Autores principales: | Mahlandt, Eike K., Kreider-Letterman, Gabriel, Chertkova, Anna O., Garcia-Mata, Rafael, Goedhart, Joachim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10234108/ https://www.ncbi.nlm.nih.gov/pubmed/37226883 http://dx.doi.org/10.1242/jcs.260802 |
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